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我国慢性病毒性肝炎病人数居世界首位。目前治慢性肝炎药物主要有三大类:抗病毒剂、改善肝功能药、免疫调节剂,但尚无真正有效的药物。因此迫切需要研制治肝炎新药。如何加快治肝炎新药的研究与开发,作者认为:(1)应当加强从中草药发掘治肝炎药,中医治肝炎有不少方剂,从中挖掘有效药物的可能性很大;(2)加强抗肝炎病毒药的研究,而且需要设想新的阻断病毒复制的靶点;(3)开辟从免疫学途径寻找治慢性肝炎新药,为此需要建立新的动物模型;(4)提高临床药理研究水平,应当推行双盲法,严格化验操作,减少人为误差;(5)加强治肝炎药基础理论研究,为研制更有效的新药开辟新思路。通过以上诸方面的努力,为慢性肝炎病人找出好的新药。
China has the largest number of chronic viral hepatitis in the world. The current treatment of chronic hepatitis drugs are mainly three categories: anti-viral agents to improve liver function drugs, immunomodulators, but there is no real effective drugs. Therefore, there is an urgent need to develop new drugs to cure hepatitis. How to speed up the research and development of new drugs for treating hepatitis, the author thinks: (1) There is a great possibility that Chinese medicines should be screened to cure hepatitis and Chinese medicine to cure hepatitis; therefore, it is highly probable to dig effective drugs; (2) to strengthen anti-hepatitis virus (3) open up new immunotherapeutic approaches to find new drugs for treating chronic hepatitis, and establish a new animal model for this; (4) to improve the level of clinical pharmacology research should be (5) to strengthen the basic theory of hepatitis medicine research, open up new ideas for the development of more effective new drugs. Through all these efforts, find a good new drug for chronic hepatitis patients.