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目的：观察脑梗塞患者血小板α－颗粒膜蛋白的变化。方法：用放免法测定４０例脑梗塞患者及２０例健康者对照血小板表面及血浆内α－颗粒膜蛋白值。结果：正常对照血小板Ｇｍｐ－１４０６５０±１８０分子数／血小板，血浆Ｇｍｐ－１４０１１．７±１．９μｇ／ｍｌ，４０例脑梗塞患者Ｇｍｐ－１４０９６３±３０２分子数／血小板，血浆Ｇｍｐ－１４０３９．４±１４．９μｇ／ｍｌ。二者有显著差异。结论：脑梗塞患者血小板活性增高。
Objective: To observe the changes of platelet α-granule membrane protein in patients with cerebral infarction. Methods: The protein values of α-granule membrane in plasma and platelet of 40 patients with cerebral infarction and 20 healthy controls were determined by radioimmunoassay. Results: Gmp-140650 ± 180 molecules / platelet, Gmp-14011.7 ± 1.9μg / ml in normal controls, Gmp-140963 ± 302 molecules / platelet in plasma of 40 patients with cerebral infarction, Gmp-14039.4 ± 14.9 μg / ml. There are significant differences between the two. Conclusion: Platelet activity is increased in patients with cerebral infarction.