论文部分内容阅读
目的:评价口服超常剂量降压药治疗急性主动脉夹层并发高血压患者的临床疗效及不良反应。方法:49例急性主动脉夹层并发高血压患者,根据使用降压药的剂量分为常规剂量组和超常剂量组。记录2组患者治疗前后血压、心率以及药物不良反应的发生情况。结果:常规剂量组与超常剂量组的患者治疗后血压、心率较治疗前均叫显下降;2组不良反应的发生率相似。结论:用超常剂量的降压药治疗主动脉夹层并发高血压是安全而有效的。
OBJECTIVE: To evaluate the clinical efficacy and adverse reactions of oral hyper-dose antihypertensive drugs in the treatment of patients with essential hypertension complicated with acute aortic dissection. Methods: Forty-nine patients with acute aortic dissection complicated with hypertension were divided into two groups according to the dose of antihypertensive drugs: conventional dose group and extra-normal dose group. Record 2 groups of patients before and after treatment of blood pressure, heart rate and adverse drug reactions. Results: The blood pressure and heart rate of patients in conventional dose group and super-dose group decreased significantly after treatment compared with those before treatment. The incidence of adverse reactions in two groups was similar. CONCLUSIONS: It is safe and effective to treat hypertensive patients with aortic dissection with ultra-dose antihypertensive drugs.