论文部分内容阅读
正常乳腺细胞和其它激素反应细胞随着激素水平的波动,其基因的表达也出现相应改变,其中一些基因与肿瘤有关。已有研究表明,患有乳腺癌的妇女,在月经周期的黄体期切除肿瘤者比在滤泡期切除者的存活状况有明显改善。作者推测乳腺癌细胞的基因表达可能会随月经周期的变化而变化,其中一些基因的表达产物与肿瘤的增生和转移有关。 32名妇女经组织学证实患有侵袭性乳腺癌,腋窝淋巴结阳性或阴性,行乳腺全切和腋窝淋巴结切除。记录病人手术前上一次月经的时间。手术时间由医生和
Normal breast cells and other hormone-responsive cells undergo a corresponding change in gene expression as hormone levels fluctuate, some of which are associated with tumors. Studies have shown that in women with breast cancer, the survival of the luteal phase of the menstrual cycle is significantly better than that of the resection of the follicular phase. The authors speculate that the gene expression of breast cancer cells may change with the menstrual cycle, and some of the gene expression products are related to tumor proliferation and metastasis. Thirty-two women were confirmed histologically for invasive breast cancer and positive or negative axillary lymph nodes. Mammary glandectomy and axillary lymph node dissection were performed. Record the time of the previous menstruation before the patient’s surgery. Operating time by doctors and