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目的探讨腹腔镜联合胃镜治疗胃间质瘤(GIST)的临床效果。方法回顾性分析行腹腔镜结合胃镜治疗18例胃间质瘤患者的临床资料,其中1例在胃镜辅助下行腹腔镜胃腔内肿瘤切除术,17例行胃镜辅助下行腹腔镜胃楔形切除术。结果 18例患者均完成手术,无手术并发症和中转开腹发生。手术时间(70.3±25.3)min,术中出血(55.4±22.6)ml,术后住院(7.5±2.4)d。切除的肿瘤直径(3.3±1.7)cm,术后免疫组化结果:CD34阳性13例(72.2%),CD117阳性16例(88.9%),其中极低度风险12例,低度风险6例,无高危病例。结论腹腔镜结合胃镜治疗胃间质瘤安全可行,值得临床推广应用。
Objective To investigate the clinical effect of laparoscopy and endoscopy in the treatment of gastric stromal tumor (GIST). Methods The clinical data of 18 patients with gastric stromal tumor treated by laparoscopy combined with endoscopy were retrospectively analyzed. Among them, 1 underwent endoscopic laparoscopic intragastric tumor resection with gastroscope and 17 underwent endoscopic gastroscope assisted laparoscopic gastric wedge resection. Results All 18 patients underwent surgery without complications and laparotomy. The operation time (70.3 ± 25.3) min, intraoperative bleeding (55.4 ± 22.6) ml and postoperative hospital stay (7.5 ± 2.4) d. The diameter of tumor resected was (3.3 ± 1.7) cm. The results of immunohistochemistry showed that there were 13 cases (72.2%) positive for CD34 and 16 cases (88.9%) for CD117 positive. There were 12 cases with very low risk and 6 cases with low risk. No high-risk cases. Conclusions Laparoscopy combined with gastroscope in the treatment of gastric stromal tumor is safe and feasible, worthy of clinical application.