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目的:分析南京医科大学第一附属医院2013—2015年微生物培养中无菌标本送检情况,研究无菌标本送检对抗菌药物使用的影响。方法:对2013—2015年出院患者微生物培养中无菌标本培养阳性率情况、送检构成比情况进行描述;分析出院患者中感染患者抗菌药物使用天数的差异性。结果:连续3年无菌标本送检分别为16 859、17 946和19 911份,呈逐年升高趋势,但感染患者人均送检量未见升高趋势;胆汁培养阳性率最高,脑脊液阳性率最低;无菌标本中血培养送检量最大,构成比在50%左右,高于其他无菌标本;2014年和2015年抗菌药物使用平均天数较2013年略有增加。结论:应提高无菌标本的送检意识,充分利用无菌标本培养结果,优化抗菌药物的合理使用。
OBJECTIVE: To analyze the status of delivery of sterile samples in the first affiliated hospital of Nanjing Medical University from 2013 to 2015 and to study the influence of the delivery of sterile samples on the use of antimicrobial agents. Methods: The positive rate of the culture of sterile specimens in the discharged patients during 2013-2015 was analyzed. The difference of the number of days of antibiotics in infected patients was analyzed. Results: The results of three consecutive years of delivery of sterile specimens were 16 859, 17 946 and 19 911, showing an increasing trend year by year, but there was no increase in per capita delivery volume of infected patients; the positive rate of bile culture was highest, and the positive rate of cerebrospinal fluid The lowest was in the sterile culture specimen, the highest was the blood culture in the sterile specimen, with a composition ratio of about 50%, higher than other sterile specimens. The average days of antibacterial use in 2014 and 2015 increased slightly compared with 2013. Conclusion: Awareness of the delivery of aseptic specimens should be improved, the culture results of aseptic specimens should be fully utilized and the rational use of antimicrobial agents should be optimized.