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目的:对缬沙坦联合氢氯噻嗪治疗高血压心脏病的临床效果进行研究。方法:选取我院2014年6月-2015年9月收治的130例高血压心脏病患者,依据随机法划分为参照组与研究组各65例。参照组65例患者给予口服缬沙坦药物治疗,研究组65例患者采用缬沙坦联合氢氯噻嗪治疗。两组患者均在连续服用16周之后对两组患者临床指标进行分析比较。结果:研究组总有效率96.92%显著高于参照组总有效率的69.23%,与治疗之前相比两组患者的舒张压、收缩压以及左室高电压等指标都有明显降低,并且研究组降低的幅度远远超过参照组,差异具备统计学意义,P<0.05。结论:对高血压心脏病患者采用缬沙坦联合氢氯噻嗪治疗可取得良好的效果,且不良反应少,值得推广。
Objective: To study the clinical effect of valsartan combined with hydrochlorothiazide in the treatment of hypertensive heart disease. Methods: A total of 130 hypertensive heart patients admitted from June 2014 to September 2015 in our hospital were selected and randomly divided into the reference group (65 cases) and the study group (65 cases). In the reference group, 65 patients were given oral valsartan medication, and 65 patients in the study group were treated with valsartan combined with hydrochlorothiazide. Two groups of patients after taking 16 consecutive weeks of clinical indicators of the two groups were analyzed and compared. Results: The total effective rate was 96.92% in the study group was significantly higher than 69.23% of the total effective rate in the reference group, diastolic blood pressure, systolic blood pressure and left ventricular high voltage and other indicators were significantly decreased in both groups compared with before treatment, and the study group The extent of decrease was much more than the reference group, the difference was statistically significant (P <0.05). Conclusion: Valsartan combined with hydrochlorothiazide in patients with hypertensive heart disease can achieve good results with less adverse reactions, which is worth promoting.