Increased Cthrcl Activates Normal Fibroblasts and Suppresses Keloid Fibroblasts by Inhibiting TGF-β/

• 作 者: Meng-jie ZHAO Si-yuan CHEN Xia
• 机 构: DepartmentofDermatology,DepartmentofDermatology,DepartmentofDermatologyandSkinScience
• 出 处: 当代医学科学(英文)
• 发表日期: 2018年5期
• 关键词: KELOID Collagen triple HELIX REPEAT containing protein 1 TGF-Β YAP
• 基金项目: This work was supported by the National Natural Science Foundation of China (No.81472886 and No. 81172588).

Keloid may induce severe impairment of life quality for the patients,although keloid is a cutaneous benign tumor.Collagen triple helix repeat containing protein 1 (Cthrc1) was identified as a novel gene that was originally found in adventitial fibroblasts