论文部分内容阅读
从1947年开始,对明尼阿波列斯和圣保罗两市的284名45～55岁男性商人和职员作了冠心病的前瞻性研究,每年定期复查,1953年、1955年开始并对260例被检者进行血清α-脂蛋白(HDL)胆固醇测定。本文报道该组至1978年止的冠心病死亡率及其他病因死亡率。本组可以代表美国白种中产阶级男性,其血压(平均收缩压126.8毫米汞柱、(血清胆固醇)平均228.8毫克/分升)以及吸烟习惯(24%每人吸烟一包以上)等均较一般低,故冠心病易患性亦低于一般水平。随访开始时的α-脂蛋白胆固醇水平为46.0±12.2毫克/分升,此值与 Framingham 地区报告的50～59岁平均α-脂蛋白胆固醇为45.2毫克/分升相一致。
Beginning in 1947, 284 prospective 452-year-old male traders and staff in Minneapolis and St. Paul conducted a prospective coronary heart disease study, reviewed annually, beginning in 1953 and beginning in 1955 with 260 cases of being The semen performed serum alpha-lipoprotein (HDL) cholesterol assay. This article reports the group until 1978, the death rate of coronary heart disease and other causes of death. This group is representative of white, middle-class men in the United States whose blood pressure (average systolic blood pressure 126.8 mmHg, (serum cholesterol) average 228.8 mg / dL) and smoking habit (24% smoking more than one pack) Low, so coronary heart disease susceptibility is also lower than the average level. The alpha-lipoprotein cholesterol level at the start of follow-up was 46.0 ± 12.2 mg / dL, consistent with an average of 45.2 mg / dL of 50- to 59-year-old reported a-lipoprotein cholesterol in Framingham.