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目的比较三种梅毒血清学实验室诊断方法的准确性及在临床的应用价值。方法应用甲苯胺红不加热血清学试验(TRUST),梅毒密螺旋体血凝试验(TPHA)及酶联免疫吸附试验(TP-ELISA)检测280例患者血清。结果TRUST、TPHA与ELISA方法特异性及灵敏度分别为95.4%、98.4%和98.9%,TPHA和ELISA明显优于TRUST法(P<0.01)。结论ELISA方法准确性及优势为目前梅毒学检测的首选方法。
Objective To compare the diagnostic accuracy of three syphilis serological laboratory methods and their clinical value. Methods 280 cases of serum were detected by TRUST, TPHA and TP-ELISA. Results The specificity and sensitivity of TRUST, TPHA and ELISA were 95.4%, 98.4% and 98.9% respectively. TPHA and ELISA were significantly better than TRUST (P <0.01). Conclusion The accuracy and advantage of ELISA method is the first choice of syphilis test.