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目的探讨宫颈上皮内瘤变(CIN)合理的确诊及治疗方法 ,为患者提供更好的治疗手段。方法 58例阴道镜下宫颈活检初诊为重度不典型增生或宫颈原位癌收入院治疗的患者,随机分为观察组和对照组,各29例。观察组患者进行宫颈锥切术,对照组患者采用常规手术。进行宫颈锥切,通过锥切术后病理检查宫颈活检病变级别是否升高。结果观察组在手术后病理检查与手术前相比得到明显的改善,总有效率为93.10%。对照组在手术后进行病理检查总效率为72.41%,治疗总有效率明显低于观察组,差异具有统计学意义(P<0.05)。结论宫颈锥切术是诊断宫颈上皮内瘤变的金标准,不能被阴道镜下宫颈活检所取代。锥切术亦可作宫颈炎的首选治疗方法。在临床医学上可广泛推广。
Objective To investigate the reasonable diagnosis and treatment of cervical intraepithelial neoplasia (CIN) and to provide better treatment for patients. Methods Fifty-eight patients underwent primary colposcopic biopsy under colposcopy for severe atypical hyperplasia or cervical carcinoma in situ were randomly divided into observation group and control group, with 29 cases in each group. Patients in the observation group underwent cervical conization, and patients in the control group received conventional surgery. Cervical conization, pathological examination by conization after cervical biopsy lesions grade is elevated. Results The observation group had a significant improvement in postoperative pathology compared with that before operation, with a total effective rate of 93.10%. The total effective rate of the control group after operation was 72.41%, the total effective rate was significantly lower than the observation group, the difference was statistically significant (P <0.05). Conclusions Cervical conization is the gold standard for the diagnosis of cervical intraepithelial neoplasia and can not be replaced by colposcopic biopsy. Conization can also be the preferred treatment for cervicitis. In clinical medicine can be widely promoted.