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糖化血红蛋白(HbA1c)作为反映血糖状态的稳定指标,对判断血糖控制是否达标有重要意义。然而,越来越多的循证医学证据表明,血糖波动也是影响糖尿病患者并发症发生和预后的不可忽视的指标。多次指血糖测定以及动态血糖监测是发现血糖波动的主要方法。除胰岛素外,多种口服降糖药具有明确的降低餐后血糖的作用,从而减少血糖的波动。α-糖苷酶抑制剂、格列奈类以及短效磺脲类药物是控制餐后高血糖的主要药物,且具有各自的作用特点。
HbA1c as a stable indicator of blood glucose status, to determine whether the glycemic control compliance is important. However, more and more evidence-based evidence shows that blood glucose fluctuations are also an important indicator of the occurrence and prognosis of diabetic patients. Repeatedly refer to blood glucose measurement and dynamic glucose monitoring is the main method of detecting blood glucose fluctuations. In addition to insulin, a variety of oral antidiabetic drugs have a clear role in reducing postprandial blood glucose, thereby reducing blood glucose fluctuations. α-glucosidase inhibitors, glinides and short-acting sulfonylureas are the main drugs to control postprandial hyperglycemia, and have their own characteristics.