Translational regulation of RPA2 via IRES by UNR and e IF3a

• 作 者: CUI Jia-jia WANG Lei-yun YIN J
• 机 构: DepartmentofClinicalPharmacology,InstituteofClinicalPharmacology,HunanKeyLaboratoryofPharmacogenetic
• 出 处: 中国药理学与毒理学杂志
• 发表日期: 2016年10期
• 基金项目: The project supported by National Natural Science Foundation of China(81573463)

OBJECTIVE To explore the mechanism of translation initiation regulation of RPA2 via IRES by UNR and e IF3a.METHODS Biotin pull down assay was taken to study the binding of RPA2 IRES and UNR.UNR was knocked down and overexpressed in H1299,A549 and SK-MES c