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目的观察氯雷他定联合氮斯汀鼻喷剂治疗过敏性鼻炎的临床疗效。方法选择医院耳鼻喉科过敏性鼻炎患者100例随机分为A、B 2组各50例。A组给予氮斯汀鼻喷剂治疗;B组在A组基础上给予氯雷他定口服治疗。比较2组总有效率、症状积分及不良反应。结果 B组总有效率为100.00%显著高于A组的78.00%,差异有统计学意义(P<0.05)。2组治疗前各项症状评分比较差异均无统计学意义(P>0.05),治疗后2组各项症状评分均显著降低,且B组低于A组,差异均有统计学意义(P<0.05)。B组不良反应总发生率为4.00%低于A组的22.00%(P<0.05)。结论氯雷他定联合氮斯汀鼻喷剂治疗过敏性鼻炎可显著提高疾病治疗效率,短时间内改善患者喷嚏、流涕等不适症状;且治疗安全性较高,可显著提高患者治疗依从性,缩短治疗与恢复时间,对改善患者生活质量具有重要意义。
Objective To observe the clinical efficacy of loratadine combined with azathinin nasal spray in the treatment of allergic rhinitis. Methods One hundred patients with otolaryngology allergic rhinitis were randomly divided into A and B 2 groups of 50 cases. Group A was treated with nitinastine nasal spray; Group B was given oral loratadine on the basis of group A. The total effective rate, symptom score and adverse reactions in two groups were compared. Results The total effective rate in group B was 100.00%, which was significantly higher than 78.00% in group A, the difference was statistically significant (P <0.05). There was no significant difference in symptom scores between the two groups before treatment (P> 0.05), and the symptom scores of two groups were significantly decreased after treatment, and the scores in group B were lower than those in group A (P < 0.05). The overall incidence of adverse reactions in group B was 4.00% lower than that in group A (22.00%, P <0.05). Conclusion The combination of loratadine and azathinin nasal spray in the treatment of allergic rhinitis can significantly improve the treatment efficiency of the disease and improve the sneezing, runny nose and other discomfort symptoms in a short period of time; and the higher safety of treatment can significantly improve the compliance of the patients Sex, shorten the treatment and recovery time, to improve the quality of life of patients is of great significance.