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[目的]观察高原地区不同海拔高度养路工人的细胞免疫水平。[方法]对海拔2800m、3500m、4000m3个海拔高度的养路工人进行T细胞亚群CD3、CD4、CD8、CD4/CD8和白细胞(WBC)、淋巴细胞(LY)检测。[结果]海拔4000m养路工人的CD3、CD4、CD8、CD4/CD8、WBC值增高最为明显(分别为85.46±7.18、47.25±8.62、33.25±9.55、1.58±0.69、6.94±1.65),而2800m则无明显增高。3个海拔高度工人的CD3、CD4、CD8、CD4/CD8和WBC值比较差异有统计学意义(P<0.01),各项值随海拔增高而增高(以CD3更为明显)。LY各组间比较,差异无统计学意义(P>0.05)。[结论]高原缺氧影响人体生理功能和免疫功能,因此在高原地区,做好体力劳动者的劳动和卫生保障工作是十分必要的。
[Objective] To observe the cellular immune level of road maintenance workers at different altitudes in the plateau area. [Method] T cell subsets CD3, CD4, CD8, CD4 / CD8, WBC and LY were detected in maintenance workers at elevation of 2800m, 3500m and 4000m3. [Results] The elevation of CD3, CD4, CD8, CD4 / CD8 and WBC were the most obvious among the 4000m road maintenance workers (85.46 ± 7.18,47.25 ± 8.62,33.25 ± 9.55,1.58 ± 0.69,6.94 ± 1.65 respectively) No significant increase. The differences of CD3, CD4, CD8, CD4 / CD8 and WBC in three altitude workers were statistically significant (P <0.01), and all the values increased with the elevation of altitude (more obvious with CD3). There was no significant difference between LY groups (P> 0.05). [Conclusion] The hypoxia in the plateau affects the physiological functions and immune functions of the human body. Therefore, it is necessary to do manual labor and sanitation work for the manual workers in the plateau area.