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目的评价和分析妊娠合并乙肝病毒感染对妊娠生化指标及妊娠结局的影响。方法回顾性对比分析了我院的284例妊娠合并乙肝病毒感染孕妇和221例无乙肝病毒感染孕妇的妊娠结局。依据有无肝功能异常,将孕妇分为肝功能异常组和正常组。结果 (1)与正常组相比,肝功能异常组的并发症发生率较高,肝功能异常组孕妇的胎膜早破率,胎儿早产率,产后出血几率,胎儿窘迫率,妊高征几率明显增多,(2)与正常组相比,肝功能异常组的新生儿出生体重较正常组明显降低。结论妊娠合并乙肝病毒感染孕妇对胎膜早破,胎儿早产,产后出血,胎儿窘迫,妊高征等并发症有显著影响,新生儿易出现体重降低等症状。应重视该类病例的治疗。
Objective To evaluate and analyze the influence of pregnancy complicated with hepatitis B virus infection on biochemical indexes of pregnancy and pregnancy outcome. Methods Retrospectively analyzed the pregnancy outcomes of 284 pregnant women with HBV infection and 221 pregnant women without hepatitis B virus infection from our hospital. According to the presence or absence of abnormal liver function, pregnant women were divided into liver dysfunction group and normal group. Results (1) Compared with the normal group, the incidence of complications in the group of abnormal liver function was higher. The rate of premature rupture of membranes, the rate of fetal premature birth, the rate of postpartum hemorrhage, the rate of fetal distress, the rate of pregnancy induced hypertension (2) Compared with the normal group, the birth weight of neonates with abnormal liver function was significantly lower than that of the normal group. Conclusion Pregnant women with hepatitis B virus infection have significant effects on complications such as premature rupture of membranes, premature fetus, postpartum hemorrhage, fetal distress and pregnancy-induced hypertension syndrome. Newborns are prone to lower body weight and other symptoms. Should pay attention to the treatment of such cases.