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目的 为探讨影响脑血管意外预后的有关因素,以住院病死病例作为病例组;存活病人为对照组。对华西医科大学附属第一医院神经内科的1990年至1996年297例患者作了回顾性的分析和研究。方法 全部病例资料应用国际临床流行病脑卒中协作组调查表,逐项记录,特别是对影响预后的有关重要因素如:病程、病情程度、神智状态、病型、年龄、合并症、并存症以及即往史和住院治疗等作了详细统计。并用双输法建立相关的数据库,资料分析处理采用x~2检验,非条件Logistic多元回归分析,并在STATA 5.0软件包上运行。结果 全部297例患者中,死亡者31例(10.4％),存活者266例。脑梗塞型179例(60％)。病例组中神智和语言障碍程度明显严重于对照组,并发高血压的比例亦高;但糖尿病及心脏病变致心律失常者,两组无差异。多因素分析链激酶类药和中西结合治疗有保护性作用(OR<1)。结论 提示住院患者脑卒中的病死率与年龄、梗塞类型、精神状态、高血压等有关。在常规治疗的基础上,中西医结合用药及溶栓抗凝药STK疗效较好。
Objective To explore the factors that affect the prognosis of cerebrovascular accident, with in-hospital death cases as the case group and the surviving patients as the control group. A retrospective analysis and study was performed on 297 patients from 1990 to 1996 in Department of Neurology, First Affiliated Hospital of Huaxi Medical University. Methods The data of all cases were recorded one by one according to the questionnaire of international clinical epidemic stroke stroke group, especially the important factors influencing prognosis such as the course of disease, the degree of illness, the state of mind, the disease type, the age, the complication, the coexisting disease and That is, to the history and hospital treatment made detailed statistics. The two databases were established by using the two-input method. Data analysis and processing were performed by x ~ 2 test and non-conditional logistic multiple regression analysis, and run on STATA 5.0 software package. Results Of all 297 patients, 31 (10.4%) died and 266 survived. 179 cases of cerebral infarction (60%). In the case group, the degree of mental retardation and language disorder were significantly higher than that of the control group, and the rate of hypertension was also high. However, there was no difference between the two groups in diabetes and cardiac arrhythmias. Multivariate analysis streptokinase and Chinese and Western combination therapy has a protective effect (OR <1). The conclusions suggest that the mortality rate of stroke in hospitalized patients is related to age, type of infarction, mental state and hypertension. On the basis of routine treatment, Integrative Medicine and thrombolytic anticoagulant STK better effect.