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目的探讨糖尿病患者冠状动脉斑块的MSCT影像学特点,以及hsCRP在预测斑块稳定性中的作用。方法2008年6月—2008年11月因不稳定心绞痛行CTA检查的254例患者,按照有无糖尿病分为2组,检测生化指标和hsCRP,比较CTA影像学上冠脉病变情况和钙化特点。结果糖尿病组血浆hsCRP水平[(4.79±2.57)mg/L]高于非糖尿病组[(2.18±1.36)mg/L],差异有统计学意义(P<0.05)。糖尿病组三支血管病变比率为34.9%,钙化病变比率为64.2%,糖尿病组二者比率分别为14.5%和35.9%,差异有统计学意义(均P<0.05)。结论糖尿病组患者CTA影像较非糖尿病组患者更弥漫,钙化更明显,血浆炎症介质水平hsCRP升高。
Objective To investigate the MSCT features of coronary plaque in diabetic patients and the role of hsCRP in predicting plaque stability. Methods From June 2008 to November 2008, 254 patients with unstable angina undergoing CTA were divided into two groups according to their diabetes mellitus. Biochemical indexes and hsCRP were compared. CTA lesions and calcifications were compared. Results The plasma levels of hsCRP in diabetic group (4.79 ± 2.57 mg / L) were significantly higher than those in non-diabetic patients (2.18 ± 1.36 mg / L) (P <0.05). The rate of three vessel diseases in diabetic group was 34.9%, the rate of calcified lesion was 64.2%, and the rate of diabetic group was 14.5% and 35.9%, respectively (all P <0.05). Conclusion Compared with non-diabetic patients, CTA images in patients with diabetes mellitus are more diffuse, calcification is more obvious, and hsCRP in plasma inflammatory mediators is increased.