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目的:探讨老年高血压患者颈动脉病变与脉压(PP)及脉压指数(PPI)的关系。方法将122例老年原发性高血压患者按颈动脉超声分为正常组和颈动脉斑块组,采用无创动态血压分别测定24h、白天及夜间平均PP、PPI。结果颈动脉斑块组PP及PPI均较颈动脉正常组增高(P<0.05)。两组内昼夜PPI差异均有统计学意义(P<0.05)。结论PP及PPI增大是致颈动脉硬化的危险因素。监测PP及PPI为早期发现和积极干预动脉硬化提供简便、有效手段。
Objective: To investigate the relationship between carotid artery disease and pulse pressure (PP) and pulse pressure index (PPI) in elderly patients with hypertension. Methods 122 elderly patients with essential hypertension were divided into normal group and carotid artery plaque group by carotid artery ultrasound. Noninvasive ambulatory blood pressure was used to measure the average PP, PPI in 24h, daytime and nighttime respectively. Results The carotid plaque group PP and PPI were higher than the normal carotid artery group (P <0.05). PPI differences between the two groups were statistically significant (P <0.05). Conclusions Increased PP and PPI are the risk factors of carotid atherosclerosis. Monitoring PP and PPI provides a simple and effective means for early detection and active intervention of atherosclerosis.