论文部分内容阅读
目的:探讨乌体林斯对耐多药肺结核辅助治疗的临床疗效。方法:对痰结核杆菌药敏实验证实(至少耐INH、RFP两种药物)的60例患者,采用随机配对方法分为化疗加乌体林斯治疗组及单纯化疗对照组,化疗前、化疗开始后前3个月每月及以后每3个月进行痰结核菌涂片及培养检测,X线检查,记录痰菌阴转及胸片病灶变化情况。化疗前及乌体林斯治疗结束后2周抽血检测T淋巴细胞亚群和细胞因子IFN-v、IL-10水平。治疗过程中观察病情变化及药物不良反应。结果:(1)治疗3、6、9个月时治疗组痰菌阴转率为56.7％,
Objective: To investigate the clinical efficacy of radioulin on multidrug-resistant pulmonary tuberculosis adjuvant therapy. Methods: 60 cases of sputum Mycobacterium tuberculosis susceptibility test (at least resistant to INH, RFP two drugs) of 60 patients were randomly paired method divided into chemotherapy plus Wu Lin tablets treatment group and chemotherapy alone control group before chemotherapy, chemotherapy began After the first 3 months of the month and every 3 months after the sputum TB smear and culture tests, X-ray examination, record sputum negative conversion and chest X-ray lesions. T lymphocyte subsets and cytokines IFN-v and IL-10 levels in blood samples were measured 2 weeks after chemotherapy and before the end of treatment. The course of treatment observed changes in the condition and adverse drug reactions. Results: (1) At 3, 6 and 9 months of treatment, sputum negative conversion rate was 56.7%