nNOS-mediated protein-protein interactions:promising targets for treating neurological and neuropsyc

• 作 者: Yuanyuan Gu Dongya Zhu
• 机 构: DepartmentofPharmacology,InstitutionofStemCellandNeuroregeneration
• 出 处: 生物医学研究杂志:英文版
• 发表日期: 2021年1期
• 关键词: NNOS PSD-95 CAPON SERT protein-protein interaction neurological and neuropsychia
• 基金项目: supported by grants from National Natural Science Foundation of China (82090042, 31530091,81870912),National Key Research and Development Program of China (2016YFC1306703)

Neurological and neuropsychiatric disorders are one of the leading causes of disability worldwide and affect the health of billions of people.Nitric oxide(NO),a free gas with multitudinous bioactivities,is mainly produced from the oxidation of L-arginine