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目的探讨NT-BNP在肺源性心脏病合并二型呼吸衰竭患者中的意义。方法 57例确诊为肺心病合并二型呼吸衰竭患者分为常规治疗组和呼吸机治疗组,测定其治疗前及治疗48hNT-BNP变化,并与同年龄组健康人进行比较。结果肺心病NT-BNP明显高于健康组,肺心病组治疗前与治疗48hNT-BNP明显下降(P<0.001)。结论脑钠肽水平变化对慢性肺源性心脏病诊断及治疗有一定的临床评价意义。
Objective To investigate the significance of NT-BNP in patients with pulmonary heart disease complicated with type 2 respiratory failure. Methods Fifty-seven patients diagnosed as pulmonary heart disease complicated with type II respiratory failure were divided into routine treatment group and ventilator treatment group. The changes of NT-BNP level before treatment and after 48-hour treatment were measured and compared with those in the same age group. Results The pulmonary heart disease NT-BNP was significantly higher than the healthy group. The pulmonary heart disease group before treatment and treatment 48h NT-BNP decreased significantly (P <0.001). Conclusion The changes of brain natriuretic peptide have some clinical significance in the diagnosis and treatment of chronic cor pulmonale.