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目的观察血液透析滤过对尿毒症脑病的疗效。方法 36例尿毒症脑病患者随机分为血液透析滤过治疗组(观察组,n=19)和常规血液透析治疗组(对照组,n=17),观察两组的疗效及血清甲状旁腺激素(PTH)水平的变化。结果治疗组的治愈率、好转率分别为68.4%,26.3%,高于对照组的58.8%,17.6%,差异有统计学意义。结论尿毒症性脑病临床表现多样,及时诊治可提高存活率。HDF能有效清除尿毒症毒素,是治疗尿毒症脑病的有效治疗方法。
Objective To observe the effect of hemodiafiltration on uremic encephalopathy. Methods Thirty - six patients with uremic encephalopathy were randomly divided into hemodiafiltration group (n = 19) and conventional hemodialysis group (n = 17). The therapeutic effects and serum parathyroid hormone (PTH) level changes. Results The cure rate and improvement rate in the treatment group were 68.4% and 26.3%, respectively, which were higher than those in the control group (58.8% and 17.6%, respectively). The difference was statistically significant. Conclusion The clinical manifestations of uremic encephalopathy are diverse, timely diagnosis and treatment can improve the survival rate. HDF can effectively remove uremic toxins, is an effective treatment of uremic encephalopathy.