论文部分内容阅读
目的:通过新生儿疾病筛查发现先天性甲状腺功能减低症(CH),早期干预,避免痴呆儿。方法:筛查采用时间分辨荧光免疫法检测滤纸血斑中促甲状腺素(TSH)值,切值为TSH>9mU/L,诊断采用化学发光酶免疫分析法,检测患儿血清甲状腺功能TSHFT3FT4水平,CH诊断标准为血清TSH升高、FT4下降、FT3降低或正常。高TSH血症诊断标准为血TSH升高、FT4正常、FT3正常。结果:安徽省筛查中心2001年6月至2011年12月31日共筛查新生儿973 907例,确诊甲低535例;高TSH 58例。结论:筛查的TSH越高,甲低发生的风险越高;高发于秋冬季节。
OBJECTIVE: To identify congenital hypothyroidism (CH) through neonatal screening, early intervention and avoid dementia. Methods: TSH value was measured by time-resolved fluorescence immunoassay in TSA of TSH> 9mU / L, and the serum TSH was detected by chemiluminescence immunoassay FT3 FT4 levels, CH diagnostic criteria for elevated serum TSH, FT4 decreased, FT3 decreased or normal. High diagnostic criteria for TSH hyperlipidemia TSH, FT4 normal, FT3 normal. Results: Screening Center of Anhui Province from June 2001 to December 31, 2011 a total of 973 907 newborns were screened, 535 cases were diagnosed hypothyroidism; high TSH 58 cases. Conclusion: The higher the TSH screening, the higher the risk of hypothyroidism; high incidence in autumn and winter.