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目的评价头孢哌酮舒巴坦联合左旋氧氟沙星对自发性细菌性腹膜炎的治疗效果。方法采用随机双盲对照方法对63例肝硬化并自发性细菌性腹膜炎进行疗效观察。其中32例采用头孢哌酮舒巴坦联合左旋氧氟沙星作为观察组,31例使用其他抗菌药物作为对照组。结果观察组14 d治愈率81.3%,明显高于对照组61.8%(P<0.05)。结论头孢哌酮舒巴坦联合左旋氧氟沙星对自发性细菌性腹膜炎的治疗效果显著。
Objective To evaluate the therapeutic effect of cefoperazone and sulbactam combined with levofloxacin on spontaneous bacterial peritonitis. Methods A randomized, double-blind comparison was performed on 63 patients with cirrhosis and spontaneous bacterial peritonitis. Among them, 32 cases were treated with cefoperazone-sulbactam combined with levofloxacin as observation group and 31 cases with other antibacterials as control group. Results The 14-day cure rate in observation group was 81.3%, which was significantly higher than that in control group (61.8%, P <0.05). Conclusion Cefoperazone sulbactam combined with levofloxacin treatment of spontaneous bacterial peritonitis has a significant effect.