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研究目的在于评价两种疫苗免疫婴儿的血清学效果和接种后的反应。所用两种疫苗的滴度均为3．5LogTCID50/0．1ml．婴儿被随机分人接种E-Z0．5ml、沪1910．2ml和沪1910．5ml各组，3个组中和抗体阳转率、＞200mlu／ml阳性率均无显著性差异（x2=0．189，0.886；P＞0005）；沪1910．5ml组血凝抑制抗体的阳转率、＞200mlu／ml阳性率均高于同剂量E-Z组（X2=561，5.4；P＜0.05）。免前未测到抗体者的中和抗体、血凝抑制抗体阳转率显著地高于免前测到抗体者（X2=7．09～36．907，P＜0．01～0．001）。沪191和E-Z麻疹疫苗接种后的皮疹率分别为47.8％和16.5％，差异十分显著。未观察到严重不良反应。
The purpose of the study was to evaluate the serological and post-vaccination response of immunized infants in both vaccines. The titers of both vaccines used were 3.5 Log TCID 50 / 0.1 ml. Infants were randomized to inoculation of E-Z0.5ml, Shanghai 1910.2ml and Shanghai 1910.5ml each group, three groups of neutralizing antibody positive rate,> 200mlu / ml positive rate was no significant difference (x2 = 0. 189,0.886; P> 0005). The positive rate of hemagglutination inhibition antibody in Shanghai 1910.5ml group was higher than that of EZ group (X2 = 561,5.4; P <0.05)> 200mlu / ml. Neutralizing antibodies were not detected before antibody, hemagglutination inhibition antibody positive rate was significantly higher than the pre-test antibody (X2 = 7.09 ~ 36.907, P <0.01 ~ 0.001) . The rash rates of Shanghai 191 and E-Z measles vaccines were 47.8% and 16.5%, respectively, with significant differences. No serious adverse reactions were observed.