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目的:观察沐舒坦联合地塞米松治疗的疗效。方法:随机将我院收治的57例新生儿吸入性肺炎患儿分成3组,为基础治疗组,地塞米松组和联合组,每组各19例患儿。基础治疗组给予吸痰、吸氧,同时进行抗感染和临床对症支持治疗。地塞米松组除了使用基础治疗组的方法外还为患者提供地塞米松。联合组除了使用基础治疗组的方法外还为患者提供沐舒坦和地塞米松。将3组患儿的临床疗效进行对比,同时记录患儿的通气时间和住院时间,比较组间的差异。结果:基础组的总有效比例为25.0%,联合组的总有效比例为84.2%,地塞米松组的总有效比例为52.6%。分别进行组间比较,联合组的疗效最好,基础组的疗效最差;联合组和地塞米松组的通气时间和住院时间均比基础组短,(P<0.05),而联合组的通气时间和住院时间又均比地塞米松组短,(P<0.05)。结论:新生儿吸入性肺炎患儿的沐舒坦和地塞米松联合用药安全、有效,应大力推广。
Objective: To observe the effect of mucosolvan combined with dexamethasone. Methods: 57 cases of neonates with asymptomatic pneumonia admitted to our hospital were randomly divided into 3 groups: basic treatment group, dexamethasone group and combination group, with 19 cases in each group. Basic treatment group given suction, oxygen, at the same time anti-infective and symptomatic symptomatic supportive treatment. The dexamethasone group was given dexamethasone in addition to the basic treatment group. In addition to using the basic treatment group, the combined group also provided patients with ambroxol and dexamethasone. The clinical efficacy of 3 groups of children were compared, meanwhile, the ventilation time and hospitalization time were recorded, and the differences among groups were compared. Results: The total effective ratio of the basic group was 25.0%, the total effective ratio of the combined group was 84.2%, and the total effective ratio of the dexamethasone group was 52.6%. The efficacy of the combination group was the best, while that of the basic group was the worst. The ventilation time and hospital stay in the combined group and dexamethasone group were shorter than those in the basic group (P <0.05), while the ventilation in the combined group Both time and hospitalization were shorter than dexamethasone group (P <0.05). Conclusion: The combination of ambroxol and dexamethasone in children with neonatal aspiration pneumonia is safe and effective and should be vigorously promoted.