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目的:探讨小儿麻甘颗粒辅助西药雾化吸入治疗小儿毛细支气管炎(痰热闭肺证)的临床疗效。方法:选取104例小儿毛细支气管炎患者,随机分为对照组和治疗组各52例。对照组予西医雾化等治疗,治疗组在对照组基础上予小儿麻甘颗粒辅助治疗。观察两组治疗前后症状、体征等中医证候总积分变化,不良反应及临床疗效。结果:治疗后治疗组中医证候总积分低于对照组,差异有统计学意义(P<0.05)。不良反应率对照组为7.7%,治疗组为3.8%;组间差异无统计学意义(P>0.05);总有效率对照组为75.0%,治疗组为90.4%;组间差异有统计学意义(P<0.05)。结论:小儿麻甘颗粒辅助西药雾化吸入治疗痰热闭肺型小儿毛细支气管炎患儿,安全有效,能明显改善患儿临床症状。
Objective: To investigate the clinical curative effect of pediatric granulobronchitis (phlegm-heat closed lung syndrome) treated by atomizing inhalation of Wilo Granules in children. Methods: 104 cases of children with bronchiolitis were selected and randomly divided into control group and treatment group of 52 cases. The control group was treated with western medicine atomization and so on. The treatment group was treated with adjuvant treatment of Ma Gan granules on the basis of the control group. Before and after treatment, the symptoms and signs of traditional Chinese medicine syndromes such as changes in the total score, adverse reactions and clinical efficacy were observed. Results: After treatment, the total score of TCM syndromes in the treatment group was lower than that in the control group, with significant difference (P <0.05). The adverse reaction rate was 7.7% in the control group and 3.8% in the treatment group. There was no significant difference between the two groups (P> 0.05). The total effective rate was 75.0% in the control group and 90.4% in the treatment group. The difference was statistically significant (P <0.05). Conclusion: The adjuvant effect of Zhigangan granule in the treatment of children with bronchiolitis with phlegm-heat syndrome is safe and effective. It can significantly improve the clinical symptoms of children.