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在小麦单隐性雄性不育基因突变体“兰州核不育”小麦上，附加１条具有特殊遗传功能的外源染色体４Ｅ（来自长穗偃麦草，携有显性蓝粒和显性可育基因），获得了既带有纯合核不育基因（ｍｓｍｓ），又能自交结实，籽粒为浅蓝色的ｍｓｍｓ基因型普通小麦４Ｅ染色体单体异附加系〔２ｎ＝４２Ｗ（ｍｓｍｓ）＋１（４Ｅ）＝４３〕，该系自交后代可分离出６４．３％白粒雄性不育种子〔２ｎ＝４２Ｗ（ｍｓｍｓ）＝４２〕、３２．１％的浅蓝粒自交可结实种子〔２ｎ＝４２Ｗ（ｍｓｍｓ）＋１（４Ｅ）＝４３〕和３．６％的深蓝粒自交可结实种子〔２ｎ＝４２Ｗ（ｍｓｍｓ）＋２（４Ｅ）＝４４〕。浅蓝粒种子下一代自交后仍能分离出相应比例的白粒不育和蓝粒可育种子，由此实现了核不育的育性保持，为杂种（Ｆ１）小麦利用开辟了新途径。
In the wheat single recessive male sterility gene “Lanzhou nuclear sterile” wheat, one exogenous chromosome 4E with special genetic function (derived from long-tailed Agropyron, dominant blue and dominant fertile (Msms), but also selfing and fruiting, the grain is light blue msms genotype wheat 4E Chromosome Monosomic addition [2n = 42W (msms) +1 (4E) = 43), 64.3% male sterile seeds [2n = 42W (msms) = 42] were isolated from selfing offspring of this line, and 32.1% 2n = 42W (msms) +1 (4E) = 43] and 3.6% self-polluting seed of dark blue seeds [2n = 42W (msms) +2 (4E) = 44]. The next generation of light blue seeds can still be isolated from white male sterile and blue-fertile seeds after selfing, thus realizing the fertility maintenance of nuclear sterility and opening up a new way for the utilization of F1 hybrid wheat .