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目的:分析急性有机氟中毒患者呼吸系统损害的特点。方法:回顾性分析我院2011年集中收治的22例急性有机氟中毒患者的临床资料,着重分析患者的呼吸系统症状、肺部体征、影像学表现、肺功能的影响。结果:有机氟气体中毒呼吸系统损害主要表现为胸闷、气喘、咳嗽、呼吸困难,影像学特征为两肺渗出性病变、急性肺水肿,可并发纵膈/皮下气肿,后期可以出现肺纤维化且为可逆,对肺功能、劳动能力的影响轻微。结论:有机氟气体所致的肺损伤具有“隐匿性、爆发性、致死性”的特点,临床工作中要保持高度警惕,有条件尽可能行CT检查,并至少要留观72h,做到早诊断、早治疗,一般预后良好。
Objective: To analyze the characteristics of respiratory system damage in patients with acute organic fluorosis. Methods: The clinical data of 22 patients with acute fluorosis admitted in our hospital in 2011 were analyzed retrospectively. The respiratory symptoms, lung signs, imaging findings and pulmonary function were analyzed emphatically. Results: The organophosphate gas poisoning respiratory system damage mainly manifested as chest tightness, asthma, cough, dyspnea, imaging features of exudative pulmonary lesions, acute pulmonary edema, may be associated with mediastinum / subcutaneous emphysema, the latter may appear pulmonary fibrosis It is reversible and has a slight effect on lung function and labor ability. Conclusion: The lung injury caused by organofluorine gas has the characteristics of “occult, explosive and fatal”. The clinical work should be highly vigilant. It is necessary to carry out CT examination as far as possible and at least to observe for 72h To early diagnosis and early treatment, the general prognosis is good.