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从脂质代谢紊乱的角度来看,冠心病可看作是一种代谢性疾病,它的发病机制与内分泌功能紊乱密切相关。大量的临床、流行病学和实验研究表明,不论在糖尿病或在非糖尿病中,高胰岛素水平可导致动脉粥样硬化,高胰岛素血症是一个潜在的致冠心病危险因子。一、临床和流行病学研究 1.糖尿病、胰岛素与冠心病糖尿病是被公认的致冠心病的危险因子,糖尿病不但加速动脉粥样硬化的发展,且使其严重程度增加。糖尿病患者动脉粥样
From the perspective of lipid metabolism disorders, coronary heart disease can be seen as a metabolic disease, its pathogenesis and endocrine disorders are closely related. A large number of clinical, epidemiological and experimental studies have shown that high insulin levels lead to atherosclerosis in either diabetes or nondiabetic hyperinsulinemia as a potential risk factor for coronary heart disease. First, the clinical and epidemiological studies 1. Diabetes, insulin and coronary heart disease Diabetes mellitus is recognized as a risk factor for coronary heart disease, diabetes not only accelerate the development of atherosclerosis, and make it more serious. Diabetic patients atherosclerosis