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目的：研究腹腔置入中心静脉导管引流腹水联合泼尼松治疗结核性腹膜炎的临床疗效。方法：将47例伴有大量腹水的结核性腹膜炎患者随机分为两组：治疗组24例，采用中心静脉导管置入腹腔引流腹水并口服泼尼松；对照组23例，采用常规腹腔腔穿刺抽腹水。两组均采用3HRZE/9HRE抗结核治疗方案。结果：治疗组腹水消失时间明显短于对照组，发生肠粘连、肠梗阻小于对照组，差异有统计学意义（P＜0.05），两组副反应无明显差异（P>0.05）。结论：腹腔置管引流联合泼尼松治疗大量腹水的结核性腹膜炎疗效确切，副作用小，值得进一步推广。“,”Objective To observe the effect of central venous catheterition combined with prednisone treat tuberculous peritonitis. Methods 47 tuberculous peritonitis patients were randomly divided into two groups,the treatment group received the treatment of depositing a central venous catheter in abdominal cavity cavity and taking prednisone.group B received the treatment of removing fluid from the cavity with abdominal centesis intermittently.both groups were gived regular anti-tuberculosis therapy of 3HRZE/9HRE. Result The incidenc of ankylenteron and abdomina adhesions is less in the treatment group, and the time of pleural effusion absorption was shorter in treatment group(P0.05). Conclusion It is effective method to treat tuberculous peritonitis by central venous catheter combine prednisone, and il effect little ,worth to further clinical investigation.