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目的:观察复肾汤联合高通量血液透析治疗慢性肾功能不全尿毒症期的临床疗效。方法:将88例慢性肾功能不全尿毒症期患者,随机分成治疗组与对照组,各44例,对照组给予高通量血液透析治疗,治疗组在对照组基础上加用复肾汤,治疗4周后比较两组患者临床证候积分变化情况、临床疗效及肾功能相关指标的改善情况。结果:治疗后,治疗组临床证候积分下降情况优于对照组(P<0.05);治疗组临床总有效率88.6%高于对照组的68.2%(P<0.05);两组患者BUN、Scr及24 h尿蛋白定量较治疗前降低,Ccr水平较前上升,治疗组BUN、Scr及24 h尿蛋白定量水平低于对照组(P<0.05),Ccr值高于对照组(P<0.05)。结论:复肾汤联合高通量血液透析治疗慢性肾功能不全尿毒症期有较好的临床疗效,可改善肾功能,值得临床推广运用。
Objective: To observe the clinical efficacy of Fu Shen Tang combined with high-throughput hemodialysis in the treatment of chronic renal insufficiency uremia. Methods: 88 patients with uremia of chronic renal failure were randomly divided into treatment group and control group, 44 cases in each group. The control group was given high-flux hemodialysis. The treatment group was treated with Fu Shen Tang on the basis of the control group After 4 weeks, the change of clinical syndrome score, clinical curative effect and improvement of renal function related indexes were compared between the two groups. Results: After treatment, the score of clinical syndrome in the treatment group was significantly lower than that of the control group (P <0.05). The total clinical effective rate in the treatment group was 88.6% higher than that in the control group (68.2%, P <0.05) (P <0.05). The levels of Ccr in the treatment group were significantly lower than those in the control group (P <0.05), and the levels of Ccr in the treatment group were lower than those in the control group . Conclusion: Fu Shen Tang combined with high-throughput hemodialysis treatment of chronic renal insufficiency uremia have a better clinical efficacy, can improve renal function, it is worth promoting the use of clinical.