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安搏律定(Apridine)化学名茚满丙二胺,是一种较新的广谱强效Ⅰ型抗心律失常药,由于本药的治疗剂量与中毒剂量相当接近,易出现毒副作用,限制了该药的广泛使用。为了减轻与防止本药的不良反应,便于临床应用。1985年3月至1987年3月笔者试用小剂量安搏律定对不同病因的各种心律失常66例进行治疗观察,取得较好的效果,现报道如下。资料与方法一、病例选择患者66例,其中男30例,女36例。年龄18～73岁,平均40岁。心律失常的病因为冠心病14例,风湿性心脏病6例,慢性肺心病2例,心肌炎及其后遗症28例,心肌
Apridine chemical name indane propane diamine, is a new broad-spectrum potent type Ⅰ antiarrhythmic drugs, the dose of the drug dose and poisoning quite close, prone to side effects, restrictions The widespread use of the drug. In order to reduce and prevent the adverse reactions of this drug, to facilitate clinical application. From March 1985 to March 1987, the author tried a small dose of ambush to determine the different causes of arrhythmia 66 cases observed and achieved good results, are reported below. Materials and Methods First, the patient selection 66 cases, including 30 males and 36 females. Aged 18 to 73 years old, average 40 years old. The causes of arrhythmia were coronary heart disease in 14 cases, rheumatic heart disease in 6 cases, chronic pulmonary heart disease in 2 cases, myocarditis and its sequelae in 28 cases,