论文部分内容阅读
目的:探讨老年原发性高血压(EH)患者尿酸与尿微量蛋白的关系。方法:观察215例EH患者各尿酸水平分组之间年龄、尿微量白蛋白(ALB)、尿视黄醇结合蛋白(RBP)、尿免疫球蛋白(IgG)、血肌酐、尿素氮、TC、TG和空腹血糖的变化及其相互关系。结果:各尿酸组之间ALB、RBP、IgG和尿素氮差异有统计学意义(P<0.01或P<0.05),多因素Linear regression分析发现肌酐、尿酸是ALB和RBP的相关因子(P<0.01或P<0.05),血糖和尿酸是IgG的相关因子(均P<0.05)。结论:尿酸升高的EH患者,ALB、RBP、IgG均增加。在EH患者中升高的尿酸可能参与肾功能的损伤。
Objective: To investigate the relationship between uric acid and microalbuminuria in elderly patients with essential hypertension (EH). Methods: The changes of age, urinary albumin (ALB), urinary retinal binding protein (RBP), urinary immunoglobulin (IgG), serum creatinine, urea nitrogen, TC, TG And fasting blood glucose changes and their relationship. Results: The differences of ALB, RBP, IgG and urea nitrogen among all uric acid groups were statistically significant (P <0.01 or P <0.05). The linear regression analysis showed that creatinine and uric acid were the correlative factors of ALB and RBP Or P <0.05), blood glucose and uric acid were related factors of IgG (all P <0.05). Conclusion: ALB, RBP and IgG were all increased in patients with elevated uric acid. Elevated uric acid may be involved in renal impairment in EH patients.