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食管静脉曲张破裂出血对肝硬变患者的预后影响很大,其治疗方法甚多,药物治疗是其中之一。最近,生长抑素的应用引人注目。生长抑素的主要药理作用是抑制生长激素、促胃泌素等垂体前叶激素和各种消化道激素的分泌。1978年 Tyden 等报告了该药对循环动力学的作用,并首先静脉给药治疗食管静脉曲张出血。生长抑素和后叶加压素一样,可收缩内脏血管,减少血流量,因也使门脉血流减少,故可明显降低门脉压。据报告门脉压亢进
Esophageal variceal bleeding on the prognosis of patients with cirrhosis great impact on the treatment of many, drug treatment is one of them. Recently, the use of somatostatin attracts attention. The main pharmacological effect of somatostatin is to inhibit the secretion of growth hormone, gastrin and other pituitary hormones and various gastrointestinal hormones. In 1978, Tyden et al. Reported the effect of this drug on circulatory dynamics, and first administered intravenously to treat esophageal variceal hemorrhage. Somatostatin and vasopressin, like contraction of visceral blood vessels, reducing blood flow, because portal blood flow is also reduced, it can significantly reduce the portal pressure. Portal hypertension is reported