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目的探讨无创呼吸机辅助新活素联合小剂量呋塞米治疗急性心肌梗死合并心力衰竭对患者左室功能的影响。方法将急性心肌梗死合并心力衰竭患者228例随机分为2组,每组114例。对照组采用新活素联合小剂量呋塞米治疗,观察组在对照组治疗的基础上应用无创呼吸机辅助治疗,比较2组患者治疗前后心率、血氧饱和度、尿量、收缩压、左室射血分数(LVEF)、左室舒张末内径(LVDD)、血清脑利钠肽含量(BNP)和超敏C反应蛋白(hsCRP)的变化情况。结果 2组患者治疗后上述各项指标均显著改善(P<0.05),2组心率、血氧饱和度、尿量、收缩压、LVEF、LVDD、血清BNP、hs-CRP水平比较差异均有统计学意义(P<0.05)。结论无创呼吸机辅助新活素联合小剂量呋塞米治疗急性心肌梗死合并心力衰竭患者疗效显著,值得在临床中应用与推广。
Objective To investigate the effect of noninvasive ventilator-assisted neoactivity combined with small-dose furosemide on left ventricular function in patients with acute myocardial infarction complicated with heart failure. Methods A total of 228 acute myocardial infarction patients with heart failure were randomly divided into two groups of 114 cases. The control group received intravenous injection combined with low-dose furosemide. The observation group was given non-invasive ventilator-assisted therapy on the basis of the control group. The heart rate, oxygen saturation, urine output, systolic blood pressure, LVEF, LVDD, BNP and hsCRP were measured. Results The above indexes in both groups were significantly improved after treatment (P <0.05). There was statistical difference between the two groups in heart rate, oxygen saturation, urine output, systolic blood pressure, LVEF, LVDD, serum BNP and hs-CRP Significance (P <0.05). Conclusion Noninvasive ventilator-assisted nestimin combined with low-dose furosemide has significant curative effect in patients with acute myocardial infarction complicated with heart failure and is worthy of clinical application and promotion.