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目的：探讨与分析奥美拉唑临床应用的不良反应及对策。方法：随机选取2013年1月~2014年12月期间我院收治的消化性溃疡患者60例作为研究对象，均给予奥美拉唑治疗，用药4周后停药，并测定凝血酶原活动度及原时间，并观察与记录治疗期间的各种不良反应情况。结果：60例患者中，脱发、口干症状为14例（23.33%）、其他不良反应为4例（6.67%）。结论：在消化性溃疡的治疗中，奥美拉唑为常用药，给药期间易发生多种不良反应，应给予重视，保证用药安全。
Objective: To explore and analyze the clinical application of omeprazole adverse reactions and countermeasures. Methods: Sixty patients with peptic ulcer admitted to our hospital from January 2013 to December 2014 were selected randomly. All patients were treated with omeprazole. After 4 weeks, the drug was discontinued and the activity of prothrombin And the original time, and observe and record the various adverse reactions during treatment. Results: In 60 patients, hair loss, dry mouth symptoms were 14 cases (23.33%) and other adverse reactions were 4 cases (6.67%). Conclusion: In the treatment of peptic ulcer, omeprazole is a commonly used drug, prone to a variety of adverse reactions during the administration, should pay attention to ensure drug safety.