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A simple and efficient synthesis of highly substituted pyrroles was achieved in water medium via multi-component strategy, using amine,DMAD/DEAD as well as phenacyl bromide catalyzed by β-CD.Utilizing this protocol various pyrrole derivatives were synthesized in good to excellent yields.
A simple and efficient synthesis of highly substituted pyrroles was achieved in water medium via multi-component strategy, using amine, DMAD / DEAD as well as phenacyl bromide catalyzed by β-CD. Utilizing this protocol various pyrrole derivatives were synthesized in good to excellent yields .