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目的通过回顾性分析了解3年间我院新生儿先天畸形的发生趋势,明确其影响因素。方法:将在我院出生的先天畸形病例69例作为观察组,在同期我院分娩正常的新生儿中按照相同条件随机抽出69例作为对照。调查相关因素与先天畸形的相关性。结果:院先天畸形总发生率为11.5‰,新生儿先天畸形与孕妇年龄(χ~2=4.12,P=0.042,OR=2.6)、孕妇孕产次数(χ~2=4.75,P=0.031,OR=1.6)、孕期合并症(χ~2=10.25,P<0.01,OR=3.4)、孕期服药史(χ~2=4.49,P=0.034,OR=2.2)、吸烟危害(χ~2=5.26,P=0.018,OR=1.7)有显著相关,P<0.05。
Objective To retrospectively understand the trend of neonatal congenital deformity in our hospital during the past three years and clarify the influencing factors. Methods: 69 cases of congenital malformations born in our hospital were taken as the observation group, and 69 newborns with normal birth in the same period were randomly selected according to the same conditions as the control group. To investigate the correlation between the related factors and congenital malformations. Results: The total incidence of congenital anomalies in hospital was 11.5 ‰. The number of congenital malformations and the age of pregnant women (χ ~ 2 = 4.12, P = 0.042, OR = 2.6) (Χ ~ 2 = 4.49, P = 0.034, OR = 2.2), smoking risk (χ ~ 2 = 5.26, P = 0.018, OR = 1.7), P <0.05.