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目的:探讨液基细胞学检查(TCT)联合阴道镜下定点活检对子宫颈病变的诊断价值。方法:回顾性分析2006年3月～2008年3月在该院妇科门诊1 230例患者TCT检查结果,诊断标准采用国际防癌协会2001版TBS(the Bethesda system,TBS)分类系统,对91例细胞学诊断非典型鳞状细胞者行阴道镜下定点宫颈活检组织学诊断对照。结果:91例非典型鳞状细胞活检中鳞状细胞癌2例,CINⅢ6例,CINⅡ4例,CINⅠ9例,HPV感染18例,炎症52例。结论:TCT用于宫颈病变筛查,可明显提高宫颈癌前病变及宫颈癌的检出率,对宫颈癌早期诊断、早期治疗从而降低患者病死率有很大作用,是宫颈病变筛查的有效方法。在诊断为非典型鳞状细胞的患者中,应行阴道镜下定点活检,以避免宫颈上皮内瘤变及宫颈癌的漏诊。
Objective: To investigate the diagnostic value of liquid-based cytology (TCT) combined with colposcopy biopsy for cervical lesions. Methods: The TCT results of 1,230 gynecological clinics in our hospital from March 2006 to March 2008 were retrospectively analyzed. The diagnostic criteria were based on the TBS (TBS) classification system 2001 version. Totally 91 patients Cytological diagnosis of atypical squamous cells underwent colposcopic cervical biopsy histological diagnosis control. Results: There were 2 cases of squamous cell carcinoma in 91 cases of atypical squamous cell biopsy, 6 cases of CINⅢ, 4 cases of CINⅡ, 9 cases of CINⅠ, 18 cases of HPV infection and 52 cases of inflammation. Conclusion: TCT for cervical lesions screening can significantly improve the detection rate of cervical precancerous lesions and cervical cancer, early diagnosis of cervical cancer, early treatment and thus reduce the mortality of patients have a great role, is the effective screening of cervical lesions method. In patients diagnosed with atypical squamous cells, colposcopy biopsies should be performed to avoid cervical intraepithelial neoplasia and cervical cancer missed diagnosis.