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目的 探讨新生儿脑水肿的临床诊断标准。方法 以１００ 例经腰穿测压及１３２ 例经尸体解剖确诊的新生儿脑水肿的临床资料对照小儿急性脑水肿协作组的临床诊断标准（ 简称“标准”） 进行分析。结果 “标准”中适合新生儿的临床观察指标仅有呼吸不规律、前囟饱满、血压增高、瞳孔扩大、昏迷昏睡、抽搐和（ 或） 肌张力改变六项，１４３ 例（６１６ ％ ） 符合“标准”，７８ 例（３３６ ％ ） 达不到“标准”，猝死１１ 例（４７ ％ ） ， 临床漏诊６３ 例（ 占尸解的４７７ ％ ） ，后三者以早产儿为多。结论 在具有严重缺氧、感染等原发病的基础上，出现以上六项中的任何一项临床指标即应怀疑脑水肿，出现二项即可诊断脑水肿。
Objective To investigate the clinical diagnostic criteria of cerebral edema in neonates. Methods Clinical data of 100 children with acute cerebral edema and co-operation group (“standard”) were analyzed by clinical data of 100 cases of lumbar puncture and 132 cases of neonatal brain edema confirmed by autopsy. Results The clinical observation index suitable for neonates in the standard only showed irregular breathing, full anterior fontanel, high blood pressure, dilated pupils, unconscious lethargy, convulsions and (or) changes in muscle tension. 143 cases (61.6% According to “standard”, 78 cases (33.6%) did not reach “standard”, 11 cases (47%) died of sudden death, 63 cases missed diagnosis (477% of autopsy) More children. Conclusion On the basis of primary diseases with severe hypoxia and infection, any one of the above six clinical indicators should be suspected of cerebral edema, and two items can be used to diagnose cerebral edema.