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生育和不育是一个问题的二个方面,两者均不能偏废。1971年首由Schally等人从猪的下丘脑中分离、提纯,现已能大量人工合成的促黄体生成激素释放激素(LRH)因具有促生育和抗生育两方面的作用而引起了人们普遍的关注,研究活跃,资料很多。有关LRH及其类似物用于男性抗生育方面的概况我们已作过介绍,故本文介绍LRH及其类似物促生育方面的情况,供参考。一、诊断方面:LRH下丘脑垂体兴奋试验在男性不育症诊断方面的临床应用:已知,神经下丘脑-垂体-睾丸轴系统的完整性是维持男性正常性功能和生育力的根本保证,而其中任一环节的损害均可能导致男性性功能和生育力的异常。由于LRH对下丘脑-垂体-睾丸轴系的激素分泌及其生理效应具有特殊的调控作用,故使用LRH下丘脑-垂体兴奋试验对于男性不育症诊断应该是有帮助的。男性性激素水平不像女性有明显的周期性改变,故在各个不同的时间
Childbirth and infertility are two aspects of a problem, neither of which can be neglected. In 1971, firstly, Schally et al. Isolated and purified from the hypothalamus of pigs. Luteinizing hormone releasing hormone (LRH), which has been synthesized in large quantities, has been widely used for its potential role in both procreation and anti-fertility Concerned, active research, a lot of information. We have introduced the general situation of LRH and its analogs used in male antifertility, so this article introduces the situation of procreation of LRH and its analogues for reference. First, the diagnostic aspects: LRH hypothalamic pituitary irritation test in the diagnosis of male infertility clinical application: It is known that the integrity of the hypothalamus - pituitary - testis axis system is to maintain the normal male sexual function and fertility of the fundamental guarantee, Any one of the links of the damage may lead to male sexual dysfunction and fertility. LRH hypothalamus-pituitary excitability test should be helpful for the diagnosis of male infertility because of its special regulation of hormone secretion and its physiological effects in the hypothalamic-pituitary-testicular axis. Male sex hormone levels, unlike women have obvious cyclical changes, so at different times