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采用福建省《产前检查记录单》在孕妇初次产前检查时(孕12±2周)进行调查,项目含有血尿常规、空腹血糖(FPG)、糖化血红蛋白(HbA1c)等。并在孕妇妊娠24～28周时采用二步法诊断妊娠期糖尿病。即在孕妇妊娠24～28周时随机行50g葡萄糖负荷试验(GCT)筛查,GCT异常者(1h微量末梢血糖≥7.8mmol/L)进一步行75g口服葡萄糖耐量试验(OGTT)。结果孕妇平均年龄(27.59±3.56)岁,GCT异常413例,异常率33.52%。GDM发生率8.96%,GIGT发生率12.19%,GNGT发生率78.86%。孕妇Hb在三组之间的差异无统计学意义(P>0.05),然而孕妇年龄、初次产前检查时FPG、HbA1c、GCT异常在GDM、GIGT、GNGT三组之间的差异有统计学意义(P<0.05)。结论(1)我院GDM发生率为21.14%,高龄是高危因素。(2)随机50gGCT简便、快速,提高了孕妇的依从性。
A survey of prenatal examination in pregnant women (12 ± 2 weeks pregnant) was carried out by using the “Prenatal Examination Record Sheet” in Fujian Province. The program included hematuria, fasting blood glucose (FPG) and glycosylated hemoglobin (HbA1c). Pregnancy and pregnancy in 24 to 28 weeks using two-step method to diagnose gestational diabetes. That pregnant women 24-28 weeks of pregnancy randomized 50g glucose load test (GCT) screening, GCT abnormalities (1h trace peripheral blood glucose ≥ 7.8mmol / L) further 75g oral glucose tolerance test (OGTT). Results The average age of pregnant women (27.59 ± 3.56) years old, 413 cases of abnormal GCT, abnormal rate of 33.52%. The incidence of GDM was 8.96%, the incidence of GIGT was 12.19%, and the incidence of GNGT was 78.86%. There were no significant differences in Hb between the three groups (P> 0.05). However, there were significant differences in the age of pregnant women, FPG, HbA1c and GCT abnormalities between GDM, GIGT and GNGT groups (P <0.05). Conclusions (1) The incidence of GDM in our hospital is 21.14%, and senior citizens are risk factors. (2) random 50gGCT is simple, fast, improve the compliance of pregnant women.