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A.粉尘工人可发生恶性肿瘤,尘肺患者及粉尘工人易患肺癌,但发生的恶性肿瘤,不仅限于肺癌,石棉工人发生消化系统恶性肿瘤的危险率较高。矽尘工人癌的死亡率较正常人群增高约30%。 B.免疫异常与恶性肿瘤:尘肺患者与粉尘工人往往有细胞性免疫功能低下及体液性免疫功能亢进,是淋巴系恶性肿瘤发生的主要原因。T细胞抑制细胞突变及恶性纯株的增殖而B细胞与T细胞相反起增殖作用。 C.癌变与体内防御机构的关系,以免疫学为主:α.癌变与免疫监视学说:大部分癌细胞由正
A. Dust workers may develop malignant tumors, pneumoconiosis and dust workers susceptible to lung cancer, but the occurrence of malignant tumors, not only limited to lung cancer, asbestos workers have a higher risk of digestive system malignancies. Silicone workers have a 30% higher cancer death rate than the normal population. B. Immune abnormalities and malignant tumors: pneumoconiosis patients and dust workers often have cellular immune dysfunction and humoral immune function hyperactivity, is the main cause of lymphoid malignancies. T cells inhibit cell mutation and malignant proliferation of pure B cells and T cells play a proliferative effect. C. cancer and the relationship between body defenses to immunology-based: α. Cancer and immune surveillance say: most of the cancer cells by the positive