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目的了解克林霉素在我院使用情况,为进一步提高临床合理用药水平提供参考。方法回顾性调查218例住院患者克林霉素使用情况。结果预防用药145例(66.5%),治疗用药73例(33.5%)。不合理用药64例(29.4%),合理用药48例(22.0%),基本合理用药106例(48.6%)。不合理用药构成比,在预防用药明显高于治疗用药(38.6%vs 11.0%,P<0.05)。218例中发生不良反应12例,发生率为5.5%。结论应充分重视合理用药,尤其是预防用药的合理性。
Objective To understand the use of clindamycin in our hospital and provide a reference for further improving the clinical rational drug use. Methods A retrospective survey of 218 cases of inpatients clindamycin use. Results 145 cases of preventive medication (66.5%), 73 cases of medication (33.5%). Sixty-four cases (29.4%) were irrational, 48 cases (22.0%) were rational and 106 cases (48.6%) were rational and reasonable. The proportion of irrational drug use was significantly higher in the prophylaxis than that in the medication (38.6% vs 11.0%, P <0.05). Among 218 cases, 12 cases had adverse reactions, with a rate of 5.5%. Conclusions Should pay full attention to the rational use of drugs, especially to prevent the rationality of medication.