论文部分内容阅读
目的探讨紫杉醇与顺铂同步化疗联合三维放疗治疗中晚期食管癌的临床疗效及不良反应评价。方法将本院90例中晚期食管癌患者随机分为两组:常规放疗组45例,进行三维适形放射治疗;化放疗组45例,进行紫杉醇与顺铂同步化疗联合三维放疗治疗。对其治疗后临床疗效及不良反应进行分析总结。结果常规放疗组治疗后总有效率20例占44.4%,化放疗组治疗后总有效率26例占57.8%。化放疗组治疗后临床疗效明显好与常规放疗组。化放疗组与常规放疗组的长期生存率比较,化放疗组的长期生存率均高于常规放疗组。结论紫杉醇与顺铂同步化疗联合三维放疗治疗中晚期食管癌效果显著。
Objective To investigate the clinical efficacy and side effects of paclitaxel and cisplatin in combination with three-dimensional radiotherapy for advanced esophageal cancer. Methods 90 cases of advanced esophageal cancer patients were randomly divided into two groups: 45 cases of conventional radiotherapy group, three-dimensional conformal radiotherapy; Chemotherapy group of 45 cases, paclitaxel and cisplatin synchronous chemotherapy combined with three-dimensional radiotherapy. After treatment, the clinical efficacy and adverse reactions were analyzed and summarized. Results The total effective rate of conventional radiotherapy group was 44.4% after treatment, while the total effective rate was 57.8% after radiotherapy. Chemotherapy radiotherapy group after treatment, the clinical efficacy was significantly better than the conventional radiotherapy group. The long-term survival rates of the chemoradiotherapy group and the conventional radiotherapy group were higher than those of the conventional radiotherapy group. Conclusion paclitaxel and cisplatin simultaneous chemotherapy combined with three-dimensional radiotherapy for the treatment of advanced esophageal cancer has a significant effect.