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为了解孕妇及胎儿单纯疱疹病毒（ＨＳＶ）感染及其垂直传播状况，进而探讨孕妇及胎儿ＨＳＶ感染的危险因素，应用聚合酶链反应（ＰＣＲ）技术对２１７２例孕妇进行ＨＳＶ－ＤＮＡ检测，并对其中３４８例ＨＳＶ－ＤＮＡ阳性孕妇进一步检测绒毛或脐带血ＨＳＶ－ＤＮＡ。结果：孕妇ＨＳＶ感染率为１６０２％，不同孕期感染率无显著性差异；胎儿ＨＳＶ感染率为４８％，并随妊娠进展明显升高。年龄在２５岁至３５岁孕妇、有妊娠史孕妇、农村孕妇以及低文化程度孕妇ＨＳＶ感染的危险性高，其胎儿ＨＳＶ感染的危险性也明显增加。结论：开展对孕妇及其胎儿ＨＳＶ感染的监测具有重要意义。
In order to understand the infection of HSV and its vertical transmission in pregnant women and fetuses, and to explore the risk factors of HSV infection in pregnant women and fetuses, 2172 pregnant women were tested for HSV-DNA by polymerase chain reaction (PCR) 348 cases of HSV-DNA-positive pregnant women for further detection of villi or cord blood HSV-DNA. Results: The infection rate of HSV in pregnant women was 1602%. There was no significant difference in infection rates among different pregnancies. The infection rate of HSV in fetuses was 48%, which was significantly higher with the progress of pregnancy. Pregnant women aged 25 to 35, pregnant women with a history of pregnancy, pregnant women in rural areas and pregnant women with low educational level, high risk of HSV infection, the risk of fetal HSV infection was also significantly increased. Conclusion: To carry out the monitoring of pregnant women and their fetus HSV infection of great significance.