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青壮年脑梗塞临床并不少见、从病因、发病机理、临床表现及预后等诸方面与老年患者有众多不同.本文收集我科收治的青壮年脑梗塞125例,着重对其病因学进行分析.1 临床资料1.1 一般资料 1987年5月~1993年5月共收治50岁以下完全性缺血性卒中125例.其中1O~20岁2例.21~30岁9例,31~40岁34例,41~50岁80例.1.2 分类 根据病因不同分为以下五类:(1)早发性动脉硬化50例;(2)心源性脑梗塞,发病前有器质性心脏病或心律失常40例.其中风湿性瓣膜病16例,心律失常23例,心肌病4例,冠心病3例,心肌梗死2例.(3)非动脉硬化性血管病13例,其中多发性大动脉炎4例,烟雾病5例,胶原性疾病2例,脑外伤2例.(4)其他原因5例,其中产褥期上矢状窦血栓形成3例,经典型偏头痛发作2例.(5)原因未明17例,经临床及实验室检查未能确定病因.本资料不包括TIA及出血性脑梗塞.
It is not uncommon for young and middle-aged patients to have cerebral infarction, which is different from the elderly patients in terms of etiology, pathogenesis, clinical manifestations and prognosis, etc. In this paper, we collected 125 cases of cerebral infarction in our department and focused on the etiology. 1 Clinical data 1.1 General Information May 1987 ~ May 1993 were treated 125 cases of complete ischemic stroke less than 50 years of age, of which 1O ~ 20 years in 2 cases, 21 to 30 years in 9 cases, 31 to 40 years in 34 cases , 41 to 50 years old in 80 cases.1.2 classification according to different causes are divided into the following five categories: (1) 50 cases of early-onset atherosclerosis; (2) cardiogenic cerebral infarction, before the onset of organic heart disease or arrhythmia 40 cases, of which 16 cases of rheumatic valvular disease, 23 cases of arrhythmia, cardiomyopathy in 4 cases, 3 cases of coronary heart disease, 2 cases of myocardial infarction. (3) 13 cases of non-arteriosclerotic vascular disease, of which 4 cases of multiple arteritis , Moyamoya disease in 5 cases, collagen disease in 2 cases, brain injury in 2 cases. (4) 5 cases for other reasons, including puerperal superior sagittal sinus thrombosis in 3 cases, classic migraine attack in 2 cases. (5) unexplained 17 Cases, clinical and laboratory tests failed to determine the cause of this data does not include TIA and hemorrhagic cerebral infarction.