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促红细胞生成素(erythropoietin,EPO)是一种多功能性的细胞因子,是调节红细胞生成必需的糖蛋白型激素,最初发现由肾和胎肝产生。重组人促红细胞生成素(recombiant humanerythropoietin,rhEPO)是一种通过重组DNA技术合成的具有与天然EPO完全相同氨基酸序列和生物活性的糖蛋白[1]
Erythropoietin (EPO) is a multifunctional cytokine that is a glycoprotein hormone that is required for the regulation of erythropoiesis and was originally found in kidney and fetal liver. Recombinant human erythropoietin (rhEPO) is a kind of glycoprotein synthesized by recombinant DNA technology with the same amino acid sequence and biological activity as that of native EPO [1]